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(Appendix 1, Supplemental Figure 3), we selected a set with age (continuous), index of multiple deprivation (5 categories), underlying inflammatory diseases (time-variant), non-oral glucocorticoids (binary), cardiovascular disease (binary), chronic renal disease stage 3 or 4 (binary) and scleroderma (time-variant). Steroids cause retention of nitrogen, sodium, potassium, chloride, water and phosphorus, and decrease urinary excretion of calcium. Each ring has three pseudo mirror planes ( Figure. Doctor if you have or have ever had high blood pressure, heart disease, a heart attack, or a stroke.

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